Post-Transcriptional Regulation of Antiviral Gene Expression by N6-Methyladenosine
M. J. McFadden, A. B. R. McIntyre, H. Mourelatos, N. S. Abell, N. S. Gokhale, H. Ipas, B. Xhemalce, C. E. Mason, S. M. Horner
This study identifies N6-methyladenosine (m6A) as a post-transcriptional regulator of IFN-stimulated gene (ISG) translation during the type I IFN response, enhancing antiviral activity.
bioRxiv · Aug 5, 2020Immunology