Potential use of Sodium Butyrate (SB) as an anti-virulence agent against Vibrio cholerae targeting ToxT virulence protein.
S. Kundu, S. Das, P. Maitra, P. Halder, H. Koley, A. K. Mukhopadhyay, S.-I. MIYOSHI, S. Dutta, N. S. Chatterjee, S. Bhattacharya
This paper shows sodium butyrate suppresses virulence in Vibrio cholerae by inhibiting ToxT-DNA binding and reducing toxin production, suggesting it as an anti-virulence agent.
bioRxiv · Oct 5, 2023 · PreprintMicrobiology