Circulating levels of epirubicin cause endothelial senescence while compromising metabolic activity and vascular function
A. J. Eakin, T. McErlain, A. Burke, A. Eaton, N. Tipping, G. Allocca, C. M. Branco
This study shows that low doses of epirubicin cause endothelial senescence, reduced metabolic activity, and impaired vascular function in both cell and animal models.
bioRxiv · Jun 25, 2020Cell Biology