Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation
T. Roy, S. Ghosh, N. Piplani, L. K. Sthanam, N. Tiwary, S. Dhar, W. C. W. Konyak, S. S. Panigrahi, P. Singh, D. T. Sowpati, S. Nair, S. Kumar, P. C. Shekar, S. Sen
The paper shows that nuclear compression-induced DNA damage drives mESC differentiation via ATR-dependent Lamin A/C regulation.
bioRxiv · Mar 15, 2024Cell Biology