Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
J.-H. Lee, M. Thomsen, H. Daub, G. Thieulin-Pardo, S. C. Steinbacher, A. Sztyler, V. Dahiya, T. Neudegger, C. Dominguez, R. R. Iyer, H. A. Wilkinson, E. Monteagudo, N. V. Plotnikov, D. P. Felsenfeld, T. S. Haque, , B. C. Prasad
This study uses cryo-EM to determine multiple high-resolution structures of human MutSβ, revealing conformational changes linked to ATP/ADP binding and DNA recognition.
bioRxiv · May 8, 2023Biophysics