Author

C. Dominguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

J. W. Schwabe· 2 shared L. Fairall· 2 shared A. Baker· 1 shared A. Cruaud· 1 shared A. Dal Molin· 1 shared A. Gumovsky· 1 shared A. Hasan· 1 shared A. J. Hudson· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

J. W. Schwabe

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition

J.-H. Lee, M. Thomsen, H. Daub, G. Thieulin-Pardo, S. C. Steinbacher, A. Sztyler, V. Dahiya, T. Neudegger, C. Dominguez, R. R. Iyer, H. A. Wilkinson, E. Monteagudo, N. V. Plotnikov, D. P. Felsenfeld, T. S. Haque, , B. C. Prasad

This study uses cryo-EM to determine multiple high-resolution structures of human MutSβ, revealing conformational changes linked to ATP/ADP binding and DNA recognition.

bioRxiv · May 8, 2023Biophysics

Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

M. Tariq, T. Ikeya, N. Togashi, L. Fairall, S. Kamei, S. Mayooramurugan, L. R. Abbott, A. Hasan, C. Bueno-Alejo, S. Sukegawa, B. Romartinez-Alonso, M. A. Muro Campillo, A. J. Hudson, Y. Ito, J. W. Schwabe, , K. Tanaka

This study investigates the structural interaction between oncogenic KRas4BG12V and Rgl2RA, revealing a unique tetrameric complex formation that explains its hyperactivation of the RalA/B pathway.

bioRxiv · Oct 10, 2022Biochemistry

The Chalcidoidea bush of life - a massive radiation blurred by mutational saturation

A. Cruaud, J.-Y. Rasplus, J. Zhang, R. Burks, G. Delvare, L. Fusu, A. Gumovsky, J. T. Huber, P. Jansta, M.-D. Mitroiu, J. S. Noyes, S. van Noort, A. Baker, J. Böhmova, H. Baur, , Her

This study reconstructs the phylogeny of the hyperdiverse Chalcidoidea wasps, identifying classification issues and evolutionary shifts linked to angiosperm diversification.

bioRxiv · Sep 11, 2022 · PreprintEvolutionary Biology

An unexpected histone chaperone function for the MIER1 histone deacetylase complex

S. Wang, L. Fairall, K. Pham, T. J. Ragan, D. Vashi, M. O. Collins, C. Dominguez, J. W. Schwabe

The paper identifies an unexpected histone chaperone function for the MIER1 histone deacetylase complex, showing its ability to bind histone dimers and octamers and associate with nucleosomes.

bioRxiv · Jul 22, 2022 · PreprintBiochemistry