Coexpression of CCR7 and CXCR4 during B cell development controls CXCR4 responsiveness and bone marrow homing.
S. Mcheik, N. Van Eeckhout, C. Depoorter, C. Gales, M. Parmentier, J.-Y. Springael
This study shows that CCR7 modulates CXCR4 function during B cell development, reducing CXCR4 responsiveness and affecting bone marrow homing.
bioRxiv · Jul 2, 2019Immunology