Crest maturation at the cardiomyocyte surface contributes to a new late postnatal development stage that controls the diastolic function of the adult heart
c. karsenty, c. frugier, G. GENET, M.-H. SEGUELAS, P. Alzieu, O. Cazorla, A. Montagner, Y. Blum, c. Dubroca, J. Maupoint, B. Tramunt, M. Cauquil, T. Sulpice, S. Richard, S. Arcucci, , C. Gales
This study identifies a late postnatal developmental stage in rodents where cardiomyocyte surface crests mature, regulating diastolic function through ephrin-B1-dependent mechanisms.
bioRxiv · Feb 11, 2022Cell Biology