Transcriptional Feedback Disruption Yields Escape-Resistant Antivirals
S. Chaturvedi, M. Wolf, N. Vardi, K. Du, J. Glazier, R. Ke, M. Chan, A. Perelson, L. Weinberger
This paper develops feedback-circuit disruptors that inhibit viral replication and prevent resistance evolution in herpesviruses.
bioRxiv · Sep 15, 2020Microbiology