N. Yoder

Conserved His-Gly motif of acid-sensing ion channels resides in a reentrant loop implicated in gating and ion selectivity

This study determines the structure of chicken ASIC1a in resting and desensitized states, revealing the role of the His-Gly motif in ion permeation and gating.

Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography

This study identifies ion binding sites in chicken ASIC1a using X-ray crystallography, revealing cation and anion sites across different functional states and their roles in proton-gating modulation.