Divergent stem cell mechanisms governing the primary body axis and appendage regeneration in the axolotl
Liqun Wang, Song Li, Chao Yi, Jing Zhou, Zhouying Yong, Yan Ping Hu, Xiangyu Pan, Na Qiao, Hao Cai, Wandong Zhao, Rui Zhang, Lieke Yang, Lei Liu, Guangdun Peng, Elly Margaret Tanaka, , Ji‐Feng Fei
This study identifies divergent stem cell mechanisms in axolotl tail and limb regeneration, showing that TGF-β signaling determines lineage fate of muscle stem cells.
bioRxiv · Feb 11, 2025 · PreprintDevelopmental Biology