Author

Nadine Botherel

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Thomas DerrieniD· 4 shared benoit Hedan· 2 shared Benoît HédaniD· 2 shared Catherine Andre· 2 shared Catherine AndréiD· 2 shared Christophe HitteiD· 2 shared Edouard Cadieu· 2 shared Édouard Cadieu· 2 shared

Activity by Year

2016-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersGenetics

Thomas DerrienORCID

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Author profile →

4 papers

Recent·Most cited

The tree that hides the forest: identification of common predisposing loci in several hematopoietic cancers and several dog breeds.

Benoît Hédan, Édouard Cadieu, Maud Rimbault, Amaury Vaysse, Patrick Devauchelle, Nadine Botherel, Jérôme Abadie, Pascale Quignon, Thomas Derrien, Catherine André

This study identifies common genetic risk loci for hematopoietic cancers in dogs and humans by combining GWAS, sequencing, and imputation across breeds and cancers.

bioRxiv · Jul 23, 2020 · PreprintGenetics

Interest of circulating tumor DNA as a biomarker for canine cancers: illustration in histiocytic sarcoma, oral malignant melanoma and multicentric lymphoma

Anais Prouteau, Jerome Alexandre Denis, Pauline De Fornel, Edouard Cadieu, Thomas Derrien, Camille Kergal, Nadine Botherel, Ronan Ulve, Melanie Rault, Amira Bouzidi, Romain Francois, Laetitia Dorso, Alexandra Lespagnol, Patrick Devauchelle, Jerome Abadie, , benoit Hedan

This study detects circulating tumor DNA in dogs with cancer, showing its potential as a biomarker for diagnosis and monitoring treatment response in specific cancers.

bioRxiv · Jul 10, 2020 · PreprintCancer Biology

Characterisation and functional predictions of canine long non-coding RNAs

Céline Le Béguec, Valentin Wucher, Laëtitia Lagoutte, Édouard Cadieu, Nadine Botherel, Benoît Hédan, Clotilde De Brito, Anne-Sophie Guillory, Catherine André, Thomas Derrien, Christophe Hitte

The paper characterizes canine lncRNAs across 26 tissues, identifies tissue-specific expression patterns, and links them to transposable elements and conserved human lncRNAs.

Scientific Reports · Sep 3, 2018Peer-reviewedGenomics

FEELnc: A tool for Long non-coding RNAs annotation and its application to the dog transcriptome

Valentin Wucher, Fabrice Legeai, Benoit Hedan, Guillaume Rizk, Laetitia Lagoutte, Tosso Leeb, Vidhya Jagannathan, Edouard Cadieu, Audrey David, Hannes Lohi, Susanna Cirera, Merete Fredholm, Nadine Botherel, Peter Leegwater, Celine Le Beguec, , Thomas Derrien

FEELnc annotates long non-coding RNAs and mRNAs in the dog transcriptome, identifying 10,374 novel lncRNAs and 58,640 new mRNA transcripts.

bioRxiv · Jul 18, 2016Bioinformatics