CRISPR with independent transgenes is a safe and robust alternative to autonomous gene drives in basic research
Fillip Port, Nadine Muschalik, Simon L Bullock
The paper evaluates CRISPR/Cas reagents and designs in Drosophila, showing that optimized CRISPR with independent transgenes is efficient, versatile, and safer than autonomous gene drives.
G3 Genes|Genomes|Genetics · Jul 1, 2015Peer-reviewedGenetics