Author

Fillip Port

Primary ORCID profile (0000-0002-5157-4835 · 9 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Fillip PortiD9 papers · German Cancer Research Center

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Simon L Bullock· 3 shared Hui-Min CheniD· 1 shared Nadine Muschalik· 1 shared Tzumin LeeiD· 1 shared

Activity by Year

2014-2016 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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3 shared papersGenetics

Simon L Bullock

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3 papers

Recent·Most cited

Expansion of the CRISPR toolbox in an animal with tRNA-flanked Cas9 and Cpf1 gRNAs

Fillip Port, Simon L Bullock

This paper introduces a CRISPR system in Drosophila that allows multiple gRNAs to be produced from a single transcript, enhancing multiplexing and gene editing efficiency with Cas9 and Cpf1.

bioRxiv · Mar 31, 2016Genetics

CRISPR with independent transgenes is a safe and robust alternative to autonomous gene drives in basic research

Fillip Port, Nadine Muschalik, Simon L Bullock

The paper evaluates CRISPR/Cas reagents and designs in Drosophila, showing that optimized CRISPR with independent transgenes is efficient, versatile, and safer than autonomous gene drives.

G3 Genes|Genomes|Genetics · Jul 1, 2015Peer-reviewedGenetics

An optimized CRISPR/Cas toolbox for efficient germline and somatic genome engineering in Drosophila

Fillip Port, Hui-Min Chen, Tzumin Lee, Simon L Bullock

This paper develops an optimized CRISPR/Cas toolbox for efficient genome engineering in Drosophila, achieving high targeting efficiency and enabling precise genome modification.

Proceedings of the National Academy of Sciences · Jul 7, 2014Peer-reviewedGenetics