Development of Nanobodies as first-in-class inhibitors for the NEDP1 deNEDDylating enzyme
Naima Abidi, Hélène Trauchessec, Gholamreza Hassanzadeh‐Ghassabeh, Martine Pugnière, Serge Muyldermans, Dimitris P. Xirodimas
This paper develops and characterizes nanobodies as first-in-class inhibitors of NEDP1, showing high-affinity binding and specific inhibition of its deconjugating activity.
bioRxiv · Mar 20, 2020 · PreprintMolecular Biology