Author
Vrije Universiteit BrusselORCID 0000-0002-3678-3575Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Joar Esteban Pinto Torres, Mathieu Claes, Rik Hendrickx…·Yann G.‐J. Sterckx
This study identifies a camelid single-domain antibody that allosterically inhibits trypanosomatid pyruvate kinases, reducing parasite growth.
Naima Abidi, Hélène Trauchessec, Gholamreza Hassanzadeh‐Ghassabeh…·Dimitris P. Xirodimas
This paper develops and characterizes nanobodies as first-in-class inhibitors of NEDP1, showing high-affinity binding and specific inhibition of its deconjugating activity.
Suman De, Daniel R. Whiten, Francesco Simone Ruggeri…·David Klenerman
The paper examines soluble Aβ aggregates in CSF from AD, MCI, and healthy controls, finding stage-specific differences in aggregate size and toxicity mechanisms.
Melvin Y. Rincón, Lujia Zhou, Catherine Marneffe…·Matthew G. Holt
The paper demonstrates that AAV-delivered VHH-B9 reduces amyloid beta levels in an Alzheimer’s disease mouse model.