Author

Hélène Trauchessec

Centre National de la Recherche ScientifiqueORCID 0000-0002-1504-7042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Dimitris P. XirodimasiD· 2 shared Anton GartneriD· 1 shared Aurélien PerriniD· 1 shared Aymeric BaillyiD· 1 shared Chantal M. Maghames· 1 shared Gholamreza Hassanzadeh‐Ghassabeh· 1 shared Marina Serrano‐MaciáiD· 1 shared Martine PugnièreiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Dimitris P. XirodimasORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 20, 2020

Development of Nanobodies as first-in-class inhibitors for the NEDP1 deNEDDylating enzyme

Naima Abidi, Hélène Trauchessec, Gholamreza Hassanzadeh‐Ghassabeh…·Dimitris P. Xirodimas

This paper develops and characterizes nanobodies as first-in-class inhibitors of NEDP1, showing high-affinity binding and specific inhibition of its deconjugating activity.

4 citations

experimental assay

Molecular BiologybioRxivPreprintMar 22, 2019

The NEDD8 cycle controlled by NEDP1 upon DNA damage is a regulatory module of the HSP70 ATPase activity

Aymeric Bailly, Aurélien Perrin, Marina Serrano‐Maciá…·Dimitris P. Xirodimas

The paper shows that NEDP1 regulates the NEDD8 cycle upon DNA damage, modulating HSP70 ATPase activity to promote apoptosis and identifies this as relevant in hepatocellular carcinoma.

DOI 10.1101/583864

humanstatistical model