Electrophysiological classification of CACNA1G gene variants associated with neurodevelopmental and neurological disorders
Amaël Davakan, Leoš Cmarko, Bárbara Bruna Ribeiro Oliveira-Mendes, Claire Bernat, Najlae Boulali, Jérôme Montnach, Stephanie E. Vallee, Mary Beth Dinulos, Lydie Bürglen, Vincent Cantagrel, Norbert Weiss, Sophie Nicole, Arnaud Monteil, Michel MDW DE WAARD, Philippe Lory
This study uses automated and manual patch-clamp techniques to analyze Cav3.1 channel variants, identifying gain- and loss-of-function properties linked to neurological disorders.
Frontiers in Pharmacology · Oct 2, 2025Peer-reviewedNeuroscience