Changes in DNA double-strand break repair during aging correlate with an increase in genomic mutations.
Aditya Mojumdar, Nicola Mair, Nancy Adam, Jennifer A. Cobb
This study shows that aging leads to decreased DNA resection and increased end-joining repair, resulting in more genomic mutations in yeast.
Journal of Molecular Biology · Aug 20, 2022Peer-reviewedMolecular Biology