Aberrant 3'UTR splicing drives FUS-dependent mRNA condensates and prevents β-catenin from adherens junctions to promote cancer aggressiveness
Dawon Hong, Narae Kim, Yemin Jo, Jiwon Jeong, Insuk Sohn, Taeyoung Koo, Keunsoo Kang, Sunjoo Jeong-Yu
This study identifies aberrant 3'UTR splicing that drives FUS-dependent mRNA condensates, sequesters β-catenin in the cytoplasm, and promotes cancer aggressiveness in colorectal cancer.
bioRxiv · Jul 3, 2026 · PreprintCell Biology