BAP1 Loss Induces Senescence and Enhances the Response to Radiation Therapy and Senolytics
Abdelrahman M. Elsayed, Asmaa Mosbeh, Esraa G. Eltasawi, Pranita Hanpude, Nasir Uddin, Colleen M. Cebulla, Mohamed H. Abdel‐Rahman
This study shows BAP1 loss drives senescence in uveal melanoma and makes tumors more responsive to senolytics and radiation.
bioRxiv · Feb 9, 2026 · PreprintCancer Biology