Mitotic chromosomes fold by condensin-dependent helical winding of chromatin loop arrays
Johan Harmen Gibcus, Kumiko Samejima, Anton A. Goloborodko, Itaru Samejima, Natalia Naumova, Masato T. Kanemaki, Linfeng Xie, James R. Paulson, William C. Earnshaw, Leonid A. Mirny, Job Dekker
The paper shows mitotic chromosomes form through condensin-mediated disassembly of interphase chromatin and helical winding of loop arrays during prophase and prometaphase.
bioRxiv · Apr 20, 2018 · PreprintGenomics