Author

Natalie Biggerstaff

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Catherine Anne MarcinkiewcziD· 2 shared Kanza M. KhaniD· 2 shared Gabriel Gaudencio· 1 shared Gabrielle Bierlein-De La RosaiD· 1 shared Govindhasamy Pushpavathi SelvakumariD· 1 shared Michael E. DaileyiD· 1 shared Nagalakshmi BalasubramanianiD· 1 shared Ruixiang WangiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Catherine Anne MarcinkiewczORCID

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2 papers

Recent·Most cited

Adolescent Social Isolation Facilitates Tau Spread in Raphe Nuclei Linking Depression and Hyperalgesia in Alzheimers Disease

Nagalakshmi Balasubramanian, Gabriel Gaudencio, Kanza M. Khan, Natalie Biggerstaff, Catherine Anne Marcinkiewcz

This study shows that adolescent social isolation promotes tau spread in raphe nuclei, causing depression-like and pain-related symptoms in Alzheimer's disease.

Neurobiology of Disease · Apr 10, 2026Peer-reviewedNeuroscience

Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood

Kanza M. Khan, Gabrielle Bierlein-De La Rosa, Natalie Biggerstaff, Govindhasamy Pushpavathi Selvakumar, Ruixiang Wang, Suzanne Mason, Michael E. Dailey, Catherine Anne Marcinkiewcz

This study shows that adolescent ethanol exposure in mice leads to long-term pain sensitivity, neuroinflammation, and serotonergic deficits, with microglial activation in the dorsal raphe nucleus as a key driver.

Brain Behavior and Immunity · Jul 27, 2022Peer-reviewedNeuroscience