Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank
Ioanna Tachmazidou, Konstantinos Hatzikotoulas, Lorraine Southam, Jorge Esparza-Gordillo, Valeriia Haberland, Jie Zheng, Toby Johnson, Mine Koprulu, Eleni Zengini, Julia Steinberg, Jeremy Mark Wilkinson, Sahir Bhatnagar, Joshua Hoffman, Natalie S. Buchan, Dániel Süveges, , Eleftheria Zeggini
This study identifies 64 new genetic signals for osteoarthritis using UK Biobank data, including 52 novel loci, and highlights potential therapeutic targets with existing drugs.
Nature Genetics · Jan 21, 2019Peer-reviewedGenetics