BMP4 patterns Smad activity and generates stereotyped cell fate organisation in spinal organoids
Nathalie Duval, Célia Vaslin, Tiago Barata, Youcef El-Mokhtar Frarma, Vincent Contremoulins, Xavier Baudin, Stéphane Nedelec, Vanessa Ribes
This study shows that BMP4 exposure creates spatial BMP signalling patterns in spinal organoids, leading to stereotyped dorsal neural tube cell fate organisation in mouse and human.
Development · Jun 25, 2019Peer-reviewedDevelopmental Biology