Matrix mechanics governs mechano-metabolic adaptation across cancer grades in bladder spheroids
Sara Metwally, Dorota Gil, Justyna Śmiałek, Joanna Pabijan, Gracjan Wątor, Kajangi Gnanachandran, Massimiliano Berardi, Łukasz Kozłowski, Navdeep, Małgorzata Lekka
This study shows how bladder cancer spheroids adapt to different matrix stiffnesses through biomechanical and metabolic changes across cancer grades.
ACS Applied Materials & Interfaces · May 27, 2026Peer-reviewedBiophysics