Author

Kajangi Gnanachandran

UiT The Arctic University of NorwayORCID 0000-0003-4874-3842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Małgorzata LekkaiD· 2 shared Alessandro PodestàiD· 1 shared Dina Spigseth Hovland· 1 shared Dorota GiliD· 1 shared Ewelina LorenciD· 1 shared Gracjan WątoriD· 1 shared Jakub PospíšiliD· 1 shared Joanna PabijaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

Małgorzata LekkaORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of Pharmacology and Experimental TherapeuticsPeer-reviewedJun 4, 2026

Sublethal stress from polypharmacy modulates scavenging function and fenestrations in mouse liver sinusoidal endothelial cells

Kajangi Gnanachandran, Dina Spigseth Hovland, Jakub Pospíšil…·Peter McCourt

This study examines how polypharmacy affects liver sinusoidal endothelial cells, showing drug- and concentration-dependent changes in fenestrations and endocytosis.

1 citationtop 4%

mouseexperimental assay

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BiophysicsACS Applied Materials & InterfacesPeer-reviewedMay 27, 2026

Matrix mechanics governs mechano-metabolic adaptation across cancer grades in bladder spheroids

Sara Metwally, Dorota Gil, Justyna Śmiałek…·Małgorzata Lekka

This study shows how bladder cancer spheroids adapt to different matrix stiffnesses through biomechanical and metabolic changes across cancer grades.

3 citationstop 3%

humanexperimental assay

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BiophysicsbioRxivPreprintJul 5, 2025

Indenting multi-cellular spheroids with various cantilever tip geometry

Kajangi Gnanachandran, Ewelina Lorenc, Alessandro Podestà, Małgorzata Lekka

This study investigates how different AFM tip geometries affect the mechanical properties of multi-cellular spheroids, revealing multiscale responses and the importance of probe selection.

2 citations

humanimaging

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