Author

Neda Delgoshaie

Novartis (Switzerland)

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:yeast· 1

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Jeannette Fuchs· 1 shared Kenji ShimadaiD· 1 shared Monika Tsai-Pflugfelder· 1 shared Niloofar Davoodi Vijeh Motlagh· 1 shared Susan M. GasseriD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperMolecular Biology

Jeannette Fuchs

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 11, 2021

Destabilization of the holo-DNA Polδ by loss of Pol32 confers conditional lethality that can be suppressed by stabilizing Pol31-Pol3 interaction

Kenji Shimada, Monika Tsai-Pflugfelder, Niloofar Davoodi Vijeh Motlagh…·Susan M. Gasser

The paper identifies Pol31 mutations that suppress the lethality of Pol32 loss by stabilizing Pol3-Pol31 interaction, enhancing replication fork stability under stress.

DOI 10.1101/2021.02.11.430699

yeastexperimental assay