Human-immune-system humanized-DRAGA mice are a valuable model to study novel immunotherapies for HIV-1
Pongthorn Pumtang-on, Liliana Kopeck Thron, Negin Goodarzi, Brianna C. Davey, Emily N. Sevcik, Natalie Coleman‐Fuller, Ahmad Faisal Karim, Vaiva Vezys, Mangala Rao, Branden S. Moriarity, Mary S. Pampusch, Aaron Rendahl, Sofia A. Casares, Pamela J. Skinner
This study evaluates CAR/CXCR5-T cell therapy in HIV-infected hDRAGA mice, showing persistence and safety but no viral load reduction due to CAR/T cell HIV infection.
The Journal of Immunology · Aug 13, 2025Peer-reviewedImmunology