RhoG, Rac1 and Cdc42 cooperation in cell protrusion revealed bymultiplexed optogenetics and biosensor imaging
Frederico M. Pimenta, Jaewon Huh, Christopher M. Welch, Neha Pankow, Daniel J. Marston, Timothy C. Elston, Gaudenz M. Danuser, Klaus M. Hahn
This study uses optogenetics and biosensor imaging to show RhoG activates Rac1 and Cdc42 in cell protrusion, with RhoG's effects on protrusion partially mediated by Rac1 and some independent of it.
bioRxiv · May 13, 2026 · PreprintCell Biology