E2 ubiquitin conjugase Bendless is essential for PINK1-Park activity to regulate Mitofusin under mitochondrial stress
Rajit Narayanan Cheramangalam, Tarana Anand, Priyanka Pandey, Deepa Balasubramanian, Reshmi Varghese, Neha Singhal, Sonal Nagarkar-Jaiswal, Manish Jaiswal
The paper identifies Bendless as a regulator of PINK1-Park activity that controls Mitofusin degradation under mitochondrial stress, with implications for neuroprotection.
bioRxiv · Oct 24, 2022 · PreprintCell Biology