Integrative assessment of total and intact HIV-1 reservoir by a five-region multiplexed Rainbow digital PCR assay
Mareva Delporte, Laurens Lambrechts, Evy E. Blomme, Willem van Snippenberg, Sofie Rutsaert, Maxime Verschoore, Evelien De Smet, Ytse Noppe, Nele De Langhe, Marie‐Angélique De Scheerder, Sarah Gerlo, Linos Vandekerckhove, Wim Trypsteen
The paper develops a multiplexed digital PCR assay to quantify total and intact HIV-1 reservoirs, showing it is more specific than existing methods and enables high-throughput analysis.
Clinical Chemistry · Dec 3, 2024Peer-reviewedMolecular Biology