Author

Sofie Rutsaert

Ghent University HospitalORCID 0000-0003-4623-0939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

Linos VandekerckhoveiD· 3 shared Laurens LambrechtsiD· 2 shared Mareva DelporteiD· 2 shared Maxime VerschooreiD· 2 shared Sarah GerloiD· 2 shared Wim TrypsteeniD· 2 shared Ytse Noppe· 2 shared Andre van der Ven· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMolecular Biology

Linos VandekerckhoveORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 11, 2026

Biological aging and comorbidities are linked to HIV 1 reservoir size despite suppressive antiretroviral therapy

Mareva Delporte, Twan Otten, Kavita Mehta…·Linos Vandekerckhove

This study links HIV reservoir size to biological aging and non-AIDS comorbidities in people on suppressive antiretroviral therapy, independent of inflammation and immune history.

DOI 10.64898/2026.11.09.765455

humanbulk RNA-seq

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Molecular BiologyClinical ChemistryPeer-reviewedDec 3, 2024

Integrative assessment of total and intact HIV-1 reservoir by a five-region multiplexed Rainbow digital PCR assay

Mareva Delporte, Laurens Lambrechts, Evy E. Blomme…·Wim Trypsteen

The paper develops a multiplexed digital PCR assay to quantify total and intact HIV-1 reservoirs, showing it is more specific than existing methods and enables high-throughput analysis.

18 citationstop 5%

humanDNA methylation

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Molecular BiologyNucleic Acids ResearchPeer-reviewedSep 19, 2023

HIV-PULSE: A long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization

Laurens Lambrechts, Noah Bonine, Rita Verstraeten…·Linos Vandekerckhove

HIV-PULSE is a long-read sequencing assay that enables high-throughput, accurate characterization of HIV-1 proviral genomes without limiting dilution steps.

15 citations

long-read sequencingexperimental assay

𝕏 PostBluesky