EndoNB: A general strategy to study the internalization of cell surface proteins
An-Sofie Lenaerts, Jekaterina Kristal, T. Arima, Neza Leskovar, Narjes Zeinoddin, Leonardo Almeida-Souza
EndoNB enables analysis of surface protein turnover at endogenous levels using CRISPR/Cas9 and a cleavable probe, demonstrating its utility in studying internalization dynamics.
bioRxiv · Jun 8, 2025 · PreprintCell Biology