Epithelial Outgrowth Through Mesenchymal Rings Drives Alveologenesis
Nicholas M. Negretti, Yeongseo Son, Philip S. Crooke, Erin J. Plosa, John T. Benjamin, Christopher S. Jetter, Claire Bunn, Nicholas A. Mignemi, John J. Marini, Alice N. Hackett, Meaghan A. Ransom, David S. Nichols, Susan H. Guttentag, Heather H. Pua, Timothy S. Blackwell, , Jennifer M. S. Sucre
The paper observes alveoli formation through epithelial outgrowth and mesenchymal rings in live lung slices, challenging the existing model of airspace subdivision.
bioRxiv · Oct 6, 2022 · PreprintDevelopmental Biology