Christopher V.E. Wright

The paper maps the morphological and functional maturation of human endocrine pancreas from birth to age 10 using pediatric tissue samples and imaging techniques.

The paper identifies loss of semaphorin signaling and reduced FOXF1 expression in BPD and BPD+PH using single-cell RNA sequencing and validates findings in a murine model.

The paper observes alveoli formation through epithelial outgrowth and mesenchymal rings in live lung slices, challenging the existing model of airspace subdivision.

This study shows that Myt transcription factors prevent over-activation of stress-response genes in pancreatic β cells, maintaining their function and survival.

The paper shows that starburst amacrine cells use homotypic contacts to initiate formation of a dendritic scaffold in the retina, which is critical for direction-selective circuitry.