Author

Nick Colegrave

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:statistical model· 1

Frequent Co-Authors

Peter D Keightley· 3 shared Andrew D Morgan· 2 shared Rob W Ness· 2 shared Susanne A Kraemer· 2 shared Radhakrishnan B Vasanthakrishnan· 1 shared Robert W Ness· 1 shared

Activity by Year

2015-2015 · peak 3/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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3 shared papersGenomics

Peter D Keightley

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3 papers

Recent·Most cited

Fitness effects of new mutations in Chlamydomonas reinhardtii across two stress gradients

Susanne A Kraemer, Andrew D Morgan, Robert W Ness, Peter D Keightley, Nick Colegrave

The paper examines how mutations affect fitness in Chlamydomonas reinhardtii under different stress conditions and finds that mutational effects are stress-specific and depend on genetic background.

bioRxiv · Dec 7, 2015Genetics

Direct estimate of the spontaneous mutation rate uncovers the effects of drift and recombination in the Chlamydomonas reinhardtii plastid genome

Rob W Ness, Susanne A Kraemer, Nick Colegrave, Peter D Keightley

The paper directly estimates the mutation rate in the plastid genome of Chlamydomonas reinhardtii and shows it experiences stronger genetic drift and linkage disequilibrium compared to the nuclear genome.

bioRxiv · Nov 16, 2015Genomics

Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii

Rob W Ness, Andrew D Morgan, Radhakrishnan B Vasanthakrishnan, Nick Colegrave, Peter D Keightley

This study identifies extensive de novo mutation rate variation in Chlamydomonas reinhardtii through genome sequencing of mutation accumulation lines, revealing strain-specific and sequence-context-dependent mutability.

Genome Research · Aug 10, 2015Peer-reviewedGenomics