Author

Nick S Jones

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

Alva M. CaseyiD· 1 shared Dane M. WolfiD· 1 shared Endri MjekuiD· 1 shared Iain G Johnston· 1 shared Julien PrudentiD· 1 shared Juvid Aryaman· 1 shared Mayuko SegawaiD· 1 shared Michael P. MurphyiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Alva M. CaseyORCID

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2 papers

Recent·Most cited

Single-nucleoid imaging in whole cells defines the dynamics of the mtDNA life cycle

Dane M. Wolf, Endri Mjeku, Mayuko Segawa, Alva M. Casey, Néjma Belaadi, Robin Franklin, Michael P. Murphy, Julien Prudent, Nick S Jones, Patrick Francis Chinnery

The paper uses advanced imaging techniques to study mtDNA dynamics in quiescent human cells, revealing rapid replication and degradation rates and spatial organization of mtDNA.

bioRxiv · Jun 3, 2026 · PreprintCell Biology

Mitochondrial DNA Density Homeostasis Accounts for the Threshold Effect in Human Mitochondrial Disease

Juvid Aryaman, Iain G Johnston, Nick S Jones

The paper develops a mathematical model to explain the threshold effect in mitochondrial disease by showing cells maintain wild-type mtDNA density through volume reduction until a minimum volume is reached, after which energy production pathways are upregulated.

Biochemical Journal · Nov 24, 2017Peer-reviewedCell Biology