A new perspective on slow pacemaking in brain and heart
Arthur Fyon, Oleksandra Pavlova, Nick Schaar, Pietro Mesirca, Julien Brandoit, Sofian Ringlet, Alessio Franci, Matteo Elia Mangoni, Jochen Roeper, Guillaume Drion, Vincent Seutin, Kévin Jehasse
The paper identifies a conserved voltage-dependent pacemaker current essential for slow firing in neurons and cardiac cells, confirmed by models and experiments.
bioRxiv · Oct 30, 2025 · PreprintPhysiology