Author

Nicola Grehan

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ahmad Miremadi· 2 shared Andrew HindmarshiD· 2 shared Ayesha Noorani· 2 shared Christopher John PetersiD· 2 shared Jamie M. J. WeaveriD· 2 shared Jason CrawteiD· 2 shared Lawrence BoweriD· 2 shared Maria SecrieriD· 2 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Ahmad Miremadi

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2 papers

Recent·Most cited

Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma

Ayesha Noorani, Xiaodun Li, Martin J Goddard, Jason Crawte, Ludmil B. Alexandrov, Maria Secrier, Matthew Eldridge, Lawrence Bower, Jamie M. J. Weaver, Pierre Lao-Sirieix, Iñigo Martincorena, Irene Debiram–Beecham, Nicola Grehan, Shona MacRae, Shalini Malhotra, , Rebecca Claire Fitzgerald

The paper uses whole genome sequencing and phylogenetic analysis to show that metastases in esophageal adenocarcinoma spread rapidly through a clonal diaspora model.

Nature Genetics · Jan 1, 2020Peer-reviewedGenomics

Low-cost and clinically applicable copy number profiling using repeat DNA

Sam Abujudeh, Sebastian S. Zeki, MCV van Lanschot, Mark Pusung, Jamie M. J. Weaver, X Li, A Noorani, AJ Metz, Jan Bornschein, Lawrence Bower, Ahmad Miremadi, Rebecca Claire Fitzgerald, Edward R. Morrissey, Andy G. Lynch, Ayesha Noorani, , Richard Calvin Turkington

The paper introduces conliga, a method for inferring high-resolution SCNA profiles from a low-cost and simple assay, addressing the need for affordable SCNA analysis in clinical settings.

bioRxiv · Aug 19, 2018 · PreprintGenomics