Differential activation of p53-Lamin A/C and p16-RB mediated senescence pathways in trophoblast from pregnancies complicated by type A2 Gestational Diabetes Mellitus
Leena Kadam, Kaylee Chan, Kylia Ahuna, Nicole E. Marshall, Leslie Myatt
This study examines senescence pathways in trophoblasts from GDM pregnancies, finding sexually dimorphic dysregulation of p21, p16-RB, and p53-Lamin A/C pathways affecting trophoblast function.
The FASEB Journal · Jan 2, 2026Peer-reviewedCell Biology