NeuroscienceNeurobiology of DiseasePeer-reviewed
Human and Rodent Temporal Lobe Epilepsy is Characterized by Changes in O-GlcNAc Homeostasis that can be Reversed to Dampen Epileptiform Activity
Richard G. Sánchez, R. Ryley Parrish, Megan C. Rich…·Farah D. Lubin
This study shows that O-GlcNAc homeostasis is disrupted in TLE and that inhibiting OGA can reverse these changes and reduce seizures.