Farah D. Lubin

The paper investigates DNA 5-hydroxymethylation (5-hmC) changes in TLE patients and a rat model, finding reduced 5-hmC levels and specific gene associations, with Tet1 manipulation affecting seizure outcomes.

This study shows that Neat1 overexpression in astrocytes of male AD mice contributes to memory deficits by promoting astrocyte dysfunction, not through neuronal activity changes.

This paper develops a noninvasive optogenetic system using radioluminescent particles and focused ultrasound to deliver light-sensitive proteins to brain regions without invasive procedures.

This paper demonstrates a method for noninvasive, temporally controlled drug delivery to the rat brain using focused ultrasound and MRI-visible albumin nanoclusters.

This study shows that lncRNA Neat1 regulates histone methylation and affects memory formation, with suppression improving memory in both young and old mice.

This study shows that O-GlcNAc homeostasis is disrupted in TLE and that inhibiting OGA can reverse these changes and reduce seizures.