Absence of testes at puberty impacts functional development of nigrostriatal but not mesoaccumbal dopamine terminals in a wild-derived mouse
Jaewan Mun, Samantha Jackson, George S. Prounis, Chayarndorn Phumsatitpong, Niloofar Motahari, Lance J. Kriegsfeld, Markita Patricia Landry, Linda Wilbrecht
This study investigates how prepubertal gonadectomy affects dopamine release in the nigrostriatal and mesoaccumbal systems of wild-derived mice, finding reduced release in the nigrostriatal system but not the mesoaccumbal.
bioRxiv · May 16, 2025 · PreprintNeuroscience