Markita Patricia Landry

Acute partner loss enhances social motivation and nucleus accumbens dopamine release in prairie voles

This study shows that losing a partner increases social motivation and dopamine release in prairie voles, indicating rapid adaptation in reward circuits following social loss.

DNA-Programmed Condensate-Membrane Wetting and Cellular Internalization

This study designs DNA condensates that control their interaction with cell membranes, showing that internalization depends on a balance between adhesion and fluidity, not just affinity.

Adapting a two-photon scanning microscope for simultaneous single-photon imaging of an infrared dopamine sensor

The paper adapts a two-photon microscope to detect both visible and near-infrared fluorescence, enabling simultaneous dopamine and calcium imaging in the retina.

Neurochemical imaging reveals changes in dopamine dynamics with photoperiod in a seasonally social vole species

The paper uses near-infrared catecholamine nanosensors to study dopamine dynamics in meadow voles under different photoperiods, finding increased dopamine release and responsiveness in social voles.

Protein corona formed on lipid nanoparticles compromises delivery efficiency of mRNA cargo

A 16-hour continuous iodixanol density gradient workflow isolates lipid nanoparticle protein coronas from human plasma and shows that vitronectin and C-reactive protein coronas impair mRNA delivery in liver cells.

Quantifying Misuse of Color in Biological Research

This study quantifies colormap misuse in biological research, finding 81% of articles and 60% of figures use misapplied colormaps.

Absence of testes at puberty impacts functional development of nigrostriatal but not mesoaccumbal dopamine terminals in a wild-derived mouse

This study investigates how prepubertal gonadectomy affects dopamine release in the nigrostriatal and mesoaccumbal systems of wild-derived mice, finding reduced release in the nigrostriatal system but not the mesoaccumbal.

Oxytocin receptor absence reduces selectivity in peer relationships and alters neurochemical release dynamics in prairie voles

This study shows that oxytocin receptor absence in prairie voles impairs peer relationship formation, stability, and reward, with reduced oxytocin release in the nucleus accumbens.

Optical Fibers Functionalized with Single-Walled Carbon Nanotubes for Flexible Fluorescent Catecholamine Detection

This paper develops flexible optical fibers functionalized with SWNT-based sensors for detecting catecholamines, showing reliable performance in clinical biofluids and brain slices.

The third alpha helix of plant homeoproteins are generally cell-penetrating to plant cells

The paper identifies plant homeoprotein third alpha helices that can penetrate plant cells, similar to animal homeoproteins, and demonstrates their use for cytosolic delivery of proteins.

Anionic polymers stabilize Cas9 ribonucleoprotein nanoparticles to improve direct protein delivery and genome editing efficiencies in plant protoplasts

This paper shows that adding anionic polymers like polyglutamic acid to protoplast transfection protocols improves CRISPR-Cas9 genome editing efficiency in plants.

AI-based Prediction of Protein Corona Composition on DNA Nanostructures

The paper develops a machine-learning model to predict protein corona composition on DNA nanostructures based on design features and protein properties.

Deep profiling of plant stress biomarkers following bacterial pathogen infection with protein corona based nano-omics

This study uses a nano-omic approach with gold nanoparticles to detect early stress biomarkers in Arabidopsis thaliana infected by bacterial pathogens, improving sensitivity over conventional proteomics.

Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules

This paper demonstrates that adding small molecules to plasma enhances nanoparticle protein corona diversity, significantly increasing the number of detectable proteins in plasma proteome profiling.

Quantifying Data Distortion in Bar Graphs in Biological Research

The paper quantifies data distortion in bar graphs across biological research and proposes guidelines to improve data visualization.

High-throughput evolution of near-infrared oxytocin nanosensors enables oxytocin imaging in mice and prairie voles

The paper develops a high-throughput method to evolve near-infrared oxytocin nanosensors for live imaging of oxytocin release in mice and prairie voles.

Identifying Neural Signatures of Dopamine Signaling with Machine Learning

This study uses machine learning to distinguish dopamine modulation features between neuroanatomical regions and stimulation strengths in adult animals, finding unique predictive features not detectable by conventional analysis.

Synaptic scale dopamine disruption in Huntington's Disease model mice imaged with near infrared catecholamine nanosensors

The paper uses near-infrared catecholamine nanosensors to image dopamine release in Huntington's Disease model mice, finding decreased dopamine hotspot number, intensity, and fidelity in late-stage disease.

A ratiometric dual color luciferase reporter for fast characterization of transcriptional regulatory elements

The paper develops a dual-color luciferase reporter system for faster and more consistent characterization of transcriptional regulatory elements in plants.

High Throughput Evolution of Near Infrared Serotonin Nanosensors

This paper develops a near-infrared serotonin nanosensor through synthetic evolution, showing high selectivity and affinity for serotonin over other compounds and enabling reversible imaging in brain slices.

Imaging Striatal Dopamine Release Using a Non-Genetically Encoded Near-Infrared Fluorescent Catecholamine Nanosensor

This paper introduces a non-genetically encoded near-infrared fluorescent nanosensor to image dopamine release in brain tissue with high spatial and temporal resolution.

Ultralarge Modulation of Single Wall Carbon Nanotube Fluorescence Mediated by Neuromodulators Adsorbed on Arrays of Oligonucleotide Rings

This paper develops an ultrasensitive nanosensor for dopamine and norepinephrine using ssDNA-SWNT conjugates and elucidates the photophysical mechanisms behind its fluorescence modulation.

Molecular Recognition of Dopamine with Dual Near Infrared Excitation-Emission Two-Photon Microscopy

This paper develops a method for deep-brain neurotransmitter imaging using two-photon excitation of near-infrared nanosensors, showing reduced scattering and improved image quality.

Stochastic Simulation Of Dopamine Neuromodulation For Implementation Of Fluorescent Neurochemical Probes In The Striatal Extracellular Space

The paper develops a stochastic model of dopamine dynamics in the striatal extracellular space to optimize fluorescent nanosensor design and imaging parameters for in vivo neuromodulation imaging.