Pro-inflammatory Pathways Contribute to Pathogenesis of Clostridioides difficile Infection in a Murine Model - A Spatial Transcriptomics Study
Niloufar Ghahari, Sanjeev Kumar Narayanan, Ahmed AbdelKhalek, Deepti Pillai
This study uses spatial transcriptomics to compare gene expression in symptomatic and asymptomatic mice infected with C. difficile, identifying upregulated IL-17 pathway genes and layer-specific differences in the intestine.
Scientific Reports · Oct 8, 2025Peer-reviewedMicrobiology