Sanjeev Kumar Narayanan

Pro-inflammatory Pathways Contribute to Pathogenesis of Clostridioides difficile Infection in a Murine Model - A Spatial Transcriptomics Study

This study uses spatial transcriptomics to compare gene expression in symptomatic and asymptomatic mice infected with C. difficile, identifying upregulated IL-17 pathway genes and layer-specific differences in the intestine.

Reduced Cdc14 phosphatase activity impairs septation, hyphal differentiation and pathogenesis and causes echinocandin hypersensitivity in Candida albicans

This paper shows that reducing Cdc14 phosphatase activity in Candida albicans impairs cell wall integrity, septation, hyphal differentiation, and virulence, making it a potential antifungal drug target.