Direct interaction between cancer cells and fibroblasts promotes early chemoresistance to standard-of-care drug therapy in small cell lung cancer (SCLC)
Nilu Dhungel, Brian Latimer, David Custis, Ana‐Maria Dragoi
This study shows direct contact between SCLC cells and fibroblasts causes early chemoresistance to etoposide and cisplatin, with idarubicin remaining effective.
bioRxiv · Apr 30, 2026 · PreprintCancer Biology