Customizable high-throughput platform for profiling cofactor recruitment to DNA to characterize cis-regulatory elements and screen non-coding single-nucleotide polymorphisms
David Bray, Heather Hook, Rose W. Zhao, Jessica L. Keenan, Ashley R. Penvose, Yemi Osayame, Nima Mohaghegh, Trevor Siggers
The paper introduces CASCADE, a high-throughput platform to profile cofactor recruitment to DNA variants, identifying key regulators and ETS sites in macrophages.
bioRxiv · Apr 21, 2020 · PreprintGenomics