Ex vivo drug testing in metastatic biopsies reveals patient-specific vulnerabilities to cancer targeting and immune activating drugs
Lukas Wöhrl, Durdam Das, Kathrin Weidele, Steffi Treitschke, Celine Baron, Dagmar Halbritter, Catherine Botteron, Florian Lüke, Nataša Stojanović Gužvić, Melanie Werner‐Klein, Dennis Christoph Harrer, Tobias Pukrop, Julia Lanznaster, Thorsten Nitsch, Thomas Südhoff, , Christian Werno
This study introduces PEDRA, an ex vivo drug response assay that identifies patient-specific treatment options in metastatic biopsies, outperforming prior therapies and informing immune responses.
bioRxiv · Feb 9, 2026 · PreprintCancer Biology